Live intracellular imaging with new, conditionally active immunofluorescence probe

Furthering the visualization of intracellular dynamics for therapeutic applications, a research team has now demonstrated precise imaging of endogenous proteins in live cells using an antigen-binding fragment (Fab)-based Quenchbody (Q-body). The Q-body probe shows antigen-dependent response and a switchable (on-off) fluorescent signaling, enabling the visualization and sorting of cells expressing p53, a tumor suppressor biomarker protein.

from Top Technology News -- ScienceDaily https://ift.tt/ZeVj1UQ