Pancreatic beta-cell boost in mice paves way for future diabetes treatments

A research team has uncovered the role of a gene that is critical to boosting the number of insulin-producing cells during the early development of the pancreas. Experiments with mouse models revealed that inhibiting the gene at the early embryonic stage doubles the number of insulin-producing cells, with cells maintained into adulthood and all mice showing normal weight. The findings could bolster diabetes research efforts and eventually lead to new replacement therapies for the disease.

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