Technique allows mapping of epigenetic information in single cells at scale

Histones are tiny proteins that bind to DNA and hold information that can help turn on or off individual genes. Researchers have developed a technique that makes it possible to examine how different versions of histones bind to the genome in tens of thousands of individual cells simultaneously. The technique was applied to the mouse brain and can be used to study epigenetics at a single-cell level in other complex tissues.

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