Light-induced modification of a carboxylic acid with an aminocyclopropenone

Researchers report that carboxylic acids, functional groups contained in biomolecules, drugs, and materials can be readily modified by light-induced organic reactions using an aminocyclopropenone. This discovery opens up new pathways for carboxylic acid modification with potential applications including determination of drug target proteins, elucidation of protein function, and synthesis of functionalized polymer materials.

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